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TMEM173/STING Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 19851-1-AP-150UL
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. STING may have translocon function, the translocon possibly being able to influence the induction of type I interferons and is also involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) thus facilitating the detection of intracellular viral RNA species as well as B-form DNA and mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. Generally seen in endoplasmic reticulum membrane, cell membrane and mitochondrion outer membrane, it is ubiquitously expressed in most of tissues.Spezifikation
TMEM173/STING | |
Polyclonal | |
Unconjugated | |
TMEM173 | |
hMITA, hSTING, Mediator of IRF3 activation, MITA, MPYS, NET23, STING, TMEM173, transmembrane protein 173 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
340061, 498840, 72512 | |
-20°C | |
Liquid |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
0.33 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
F1M391, Q3TBT3, Q86WV6 | |
TMEM173 | |
TMEM173/STING Fusion Protein Ag13921 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |