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Invitrogen™ TMEM59 Monoclonal Antibody (816004)
Mouse Monoclonal Antibody
Marke: Invitrogen™ MA561993
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Beschreibung
Reconstitute at 0.5 mg/mL in sterile PBS.
Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
Spezifikation
| TMEM59 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 5% trehalose and no preservative | |
| Q9BXS4 | |
| TMEM59 | |
| E.coli-derived recombinant human TMEM59, Met1-Asn220. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunocytochemistry | |
| 816004 | |
| Unconjugated | |
| TMEM59 | |
| 1110001M20Rik; 3110046P06Rik; AI256529; C1orf8; D4Ertd20e; DCF1; dendritic cell factor 1; HSPC001; Liver membrane-bound protein; MTDCF1; ORF18; PRO195; RGD1310313; RP4-758J24.2; Tdcf1; Thymic dendritic cell-derived factor 1; TMEM59; Transmembrane protein 59; UNQ169; UNQ169/PRO195 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 9528 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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