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Invitrogen™ TOX Recombinant Rabbit Monoclonal Antibody (HL1809)
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen™ MA556901
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Beschreibung
TOX Recombinant Monoclonal Antibody for Western Blot
TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
Spezifikation
| TOX | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| O94900 | |
| TOX | |
| Recombinant fragment of human TOX. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| HL1809 | |
| Unconjugated | |
| TOX | |
| 1700007F02Rik; KIAA0808; thymocyte selection associated high mobility group box; thymocyte selection-associated high mobility group box; thymocyte selection-associated high mobility group box protein TOX; thymocyte selection-associated HMG box; thymus high mobility group box protein TOX; TOX; TOX1 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 9760 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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