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Invitrogen™ TRBP Recombinant Rabbit Monoclonal Antibody (24GB2425)

Beschreibung
TRBP Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.
Spezifikation
Spezifikation
| Antigen | TRBP |
| Anwendungen | Flow Cytometry, Western Blot, Immunocytochemistry |
| Klassifikation | Recombinant Monoclonal |
| Klon | 24GB2425 |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gen | TARBP2 |
| Gen-Zugriffsnummer | P97473, Q15633, Q3SWU0 |
| Gen-Alias | fj51e12; HAMAP-Rule:MF_03034}; LOQS; Prbp; PRM-1 RNA-binding protein; protamine-1 RNA-binding protein; RISC-loading complex subunit tarbp2; RISC-loading complex subunit TARBP2 {ECO:0000255; TAR (HIV) RNA binding protein 2; TAR (HIV) RNA-binding protein 2; TAR (HIV) RNA-binding protein TRBP1; TAR (HIV-1) RNA binding protein 2; TAR RNA binding protein 2; TAR RNA-binding protein 2; TARBP2; TARBP2 subunit of RISC loading complex; TARBP2, RISC loading complex RNA binding subunit; trans-activation responsive RNA-binding protein; trans-activation-responsive RNA-binding protein; TRBP; TRBP1; TRBP2; wu:fj51e12; zgc:63778 |
| Gensymbole | TARBP2 |
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