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  7. 18199308

Tyrosinase Antibody (T311 + OCA1/812), Novus Biologicals™

Mouse Monoclonal Antibody

Marke:  Novus Biologicals NBP2-44686-0.02MG

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Artikelnummer. 18199308

  • 265.00 € / 0.02 Milligramm

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Beschreibung

Beschreibung

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Tyrosinase Monoclonal specifically detects Tyrosinase in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.
TRUSTED_SUSTAINABILITY
Spezifikation

Spezifikation

Tyrosinase
Monoclonal
0.2mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
CMM8, EC 1.14.18.1, LB24-AB, Monophenol monooxygenase, OCA1A, OCAIA, SHEP3, SK29-AB, Tumor rejection antigen AB, tyrosinase, tyrosinase (oculocutaneous albinism IA)
Mouse
75 kDa
0.02 mg
Lipid and Metabolism
7299
Human
Purified
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
T311 + OCA1/812
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
TYR
Recombinant tyrosinase protein (T311); Recombinant human TYR protein (OCA1/812)
Protein A or G purified
RUO
Primary
Recognizes a cluster of proteins between 70-80kDa, identified as tyrosinase. Occasionally a minor band at 55kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.
Store at 4C.
IgG
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