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Tocris Bioscience™ VTP 27999 trifluoroacetate
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Artikelnummer. 18763979
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Menge:
10 mg
Packungsgröße:
10 Milligramm
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Artikelnummer. 18763979

Marke: Tocris Bioscience™ 5563/10

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Description

Highly potent and selective renin inhibitor

VTP 27999 trifluoroacetate is a highly potent and selective renin inhibitor (IC50 = 0.47 nM). Displays >1000-fold selectivity over related and unrelated off-targets. Blocks renin-stimulated ERK1/2 phosphorylation in vascular smooth muscle cells. Exhibits a different mode of action to aliskiren (Cat. No. 5491).
TRUSTED_SUSTAINABILITY

Specifications

Chemischer Name oder Material Methyl N-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamate trifluoroacetate
CAS 1013937-63-7
Menge 10 mg
Ziel Additional Synthetic Protease Inhibitors
Summenformel C26H41ClN4O5.CF3CO2H
Formelmasse 639.1
Reinheit >97%
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