CAS RN 59937-28-9
CAS RN 59937-28-9
IUPAC Name:
1,3-bis(propan-2-yl) 2-(2H-1,3-dithiol-2-ylidene)propanedioate
Synonyme:
malotilate malotilatum 马洛替酯 kantec malotilato
Molekulargewicht (g/mol):
288.38
Summenformel:
C12H16O4S2
InChi Key:
YPIQVCUJEKAZCP-UHFFFAOYSA-N
SMILES:
CC(C)OC(=O)C(C(=O)OC(C)C)=C1SC=CS1
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Malotilate, MedChemExpress
MedChemExpress Malotilate (NKK 105), an orally active hepatotropic agent and an anti-fibrotic substance, selectively inhibits the 5-lipoxygenase (5-LOX) (IC50=4.7 μM). Malotilate prevents the development of hepatocytic injury in alcohol-pyrazole hepatitis by decreasing hepatic acetaldehyde levels and preventing the retention of transferrin in the hepatocytes.
