CAS RN 660868-91-7
CAS RN 660868-91-7
IUPAC Name:
5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl)phenyl]methoxy}thiophene-2-carboxamide
Synonyme:
5-(5,6-dimethoxy-1,3-benzodiazol-1-yl)-3-{[2-(trifluoromethyl)phenyl]methoxy}thiophene-2-carboxamide
Molekulargewicht (g/mol):
477.46
Summenformel:
C22H18F3N3O4S
InChi Key:
JSKUWFIZUALZLX-UHFFFAOYSA-N
SMILES:
COC1=C(OC)C=C2N(C=NC2=C1)C1=CC(OCC2=CC=CC=C2C(F)(F)F)=C(S1)C(N)=O
1
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2
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2
Ergebnisse
1
Tocris Bioscience™ GW 843682X
CAS: 660868-91-7 Summenformel: C22H18F3N3O4S
2
GW843682X, MedChemExpress
MedChemExpress GW843682X is a selective, ATP-competitive inhibitor of PLK1 and PLK3, with IC50s of 2.2 nM and 9.1 nM, respectively, and is also >100-fold selective against ∼30 other kinases.