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ACROBiosystems Human CD28H / IGPR-1 Protein, Fc Tag
Marke: ACROBiosystems CDH-H5251-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.6 kDa. As a result of glycosylation, the protein migrates as 45-60 kDa under reducing (R) condition, and 90-120 kDa under non-reducing (NR) condition (SDS-PASpezifikation
| AAH15655.1 | |
| 100 μg | |
| Leu 23 - Gly 150 | |
| TMIGD2,IGPR1 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 40.6 kDa | |
| Human CD28H, Fc Tag (CDH-H5251) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Gly 150 (Accession # AAH15655.1). | |
| -20°C | |
| CD28H | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |