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ACROBiosystems Human TWEAK R / TNFRSF12A Protein, Fc Tag
Marke: ACROBiosystems TNA-H526A-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14 (FN14 or FGF-inducible 14), Tweak-receptor, CD antigen CD266. TNFRSF12A contains one TNFR-Cys repeat. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A is receptor for TNFSF12/TWEAK, and is weak inducer of apoptosis in some cell types. TNFRSF12A / FN14 promotes angiogenesis and the proliferation of endothelial cells.
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 32.5 kDa. As a result of glycosylation, the protein migrates as 32-45 kDa under reducing (R) condition, and 55-80 kDa under non-reducing (NR) condition (SDS-PAGSpezifikation
| AAH02718 | |
| 100 μg | |
| Glu 28 - Trp 79 | |
| TNFRSF12A,FGF-inducible 14,FN14,TweakR,CD266 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 32.5 kDa | |
| Human TWEAK R, Fc Tag (TNA-H526a) is expressed from human 293 cells (HEK293). It contains AA Glu 28 - Trp 79 (Accession # AAH02718). | |
| -20°C | |
| TWEAK R | |
| Human | |
| 50 mM Tris, 100 mM Glycine, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |