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ACROBiosystems Biotinylated Mouse BAFFR / TNFRSF13C Protein, Fc, Avitag™

Biotinylated Protein

Marke:  ACROBiosystems BAR-M82F0-25UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15896007

  • 353.08 € / 25 Mikrogramm

Voraussichtliches Versanddatum: 03-09-2021

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Beschreibung

Beschreibung

BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 35.1 kDa. As a result of glycosylation, the protein migrates as 45-60 kDa under reducing (R) condition, and 90-116 kDa under no
Spezifikation

Spezifikation

NP_082351
HEK293
Mouse
35.1 kDa
25 µg
Ser 10 - Ala 71
BAFFR,TNFRSF13C,BROMIX,CD268,CVID4,prolixin,BAFF-R
Precision Avi
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>95% as determined by SDS-PAGE
Biotinylated Mouse BAFFR, Fc,Avitag (BAR-M82F0) is expressed from human 293 cells (HEK293). It contains AA Ser 10 - Ala 71 (Accession # NP_082351).
-20°C
BAFFR
Fc Tag and Avi Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate