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ACROBiosystems Human CD5 Protein, His Tag
Marke: ACROBiosystems CD5-H52H5-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40.5 kDa. The protein migrates as 45-53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_055022 | |
| 100 μg | |
| Arg 25 - Pro 372 | |
| CD5,LEU1 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 40.5 kDa | |
| Human CD5, His Tag (CD5-H52H5) is expressed from human 293 cells (HEK293). It contains AA Arg 25 - Pro 372 (Accession # NP_055022). | |
| -20°C | |
| CD5 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |