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ACROBiosystems Human Complement Factor D / CFD Protein, His Tag (active enzyme)
Marke: ACROBiosystems CFD-H52H8-50ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 28 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_001919.2 | |
| 50 μg | |
| Ile 26 - Ala 253 | |
| CFD,Adipsin,PFD,DF,Complement factor D | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 26.3 kDa | |
| Human Complement Factor D, His Tag (CFD-H52H8) is expressed from human 293 cells (HEK293) and active. It contains AA Ile 26 - Ala 253 (Accession # P00746-1). | |
| -20°C | |
| Complement Factor D | |
| Human | |
| 50 mM Tris, 150 mM NaCl, pH8.0 | |
| HEK293 | |
| Enzymes |