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ACROBiosystems Canine GITR / TNFRSF18 Protein, His Tag
Marke: ACROBiosystems GIR-C52H6-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 20-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_001177673.1 | |
100 μg | |
Gly 23 - Pro 154 | |
AITR,GITR,TNFRSF18,CD357 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
15.8 kDa | |
Canine GITR, His Tag (GIR-C52H6) is expressed from human 293 cells (HEK293). It contains AA Gly 23 - Pro 154 (Accession # D7F619-1). | |
-20°C | |
GITR | |
Canine | |
PBS, pH7.4 | |
HEK293 | |
Immune Checkpoint Proteins |