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ACROBiosystems Cynomolgus Complement Component C5a Protein, Tag Free
Marke: ACROBiosystems C5A-C5118-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells; C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation; C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism; C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system; C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.
This protein carries no "e;tag"e;. The protein has a calculated MW of 8.4 kDa. The protein migrates as 11 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| XP_015292262.1 | |
| 100 μg | |
| Met 678 - Arg 751 | |
| C5a,Complement Component 5 A | |
| Unconjugated | |
| Tag Free | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 8.4 kDa | |
| Cynomolgus C5a, Tag Free (C5A-C5118) is expressed from E.coli cells. It contains AA Met 678 - Arg 751 (Accession # XP_015292262.1). | |
| -20°C | |
| Complement Component C5a | |
| Cynomolgus Monkey | |
| PBS, pH7.4 | |
| E.coli | |
| Cytokines and Growth Factors |