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ACROBiosystems Human IgG1 Fc Protein, gD Tag
Marke: ACROBiosystems IG1-H52G6-50ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
This protein carries a gD tag at the C-terminus. The protein has a calculated MW of 28.9 kDa. The protein migrates as 32-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| 28.9 kDa | |
| Human IgG1 Fc, gD Tag (IG1-H52G6) is expressed from human 293 cells (HEK293). It contains AA Pro 100 - Lys 330 (Accession # P01857-1 (C103S)). | |
| -20°C | |
| IgG1 Fc | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Other Recombinant Proteins |
| 50 μg | |
| Pro 100 - Lys 330 | |
| IgG1 | |
| Unconjugated | |
| gD Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |