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ACROBiosystems Human Siglec-10 Protein, Mouse IgG2a Fc Tag, low endotoxin
low endotoxin
Marke: ACROBiosystems SI0-H525b-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 85.6 kDa. The protein migrates as 90-120 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_149121.2 | |
| 100 μg | |
| Met 17 - Thr 546 | |
| SIGLEC10,MGC126774,PRO940,Siglec10,SLG2 | |
| Unconjugated | |
| Mouse IgG Fc Tag | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 85.6 kDa | |
| Human Siglec-10, Mouse IgG2a Fc Tag, low endotoxin (SI0-H525b) is expressed from human 293 cells (HEK293). It contains AA Met 17 - Thr 546 (Accession # Q96LC7-1). | |
| -20°C | |
| Siglec-10 | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |