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ACROBiosystems Human MUC-17 Protein, His Tag
Marke: ACROBiosystems MU7-H52H3-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
This protein carries a polyhistidine tag at the C-terminus. This protein was cleaved within the SEA domain between 4243 Gly and 4244 Ser, and was cleaved into N and C-terminal fragment with calculated MW of 12.6 kDa and 18.6 kDa respectively. The proteinSpezifikation
| 31.2 kDa | |
| Human MUC-17, His Tag (MU7-H52H3) is expressed from human 293 cells (HEK293). It contains AA Arg 4131 - Leu 4390 (Accession # Q685J3-1). | |
| -20°C | |
| MUC-17 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |
| 100 μg | |
| Arg 4131 - Leu 4390 | |
| Mucin-17,MUC-17,MUC17,MUC-3,MUC3 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |