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ACROBiosystems Rabbit FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Tag Free
SPR verified
Marke: ACROBiosystems FCM-R52W5-1mg
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Rabbit FCGRT&B2M Heterodimer Protein, His Tag&Tag Free, produced by co-expression of FCGRT and B2M, has a calculated MW of 32.1 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and subunit Beta-2 microglobuSpezifikation
ABY47597.1 (FCGRT) and ALR85722.1 (B2M) | |
1 mg | |
Ala 24 - Val 297 (FCGRT) and Val 22 - Tyr 120 (B2M) | |
FcRn,FCGRT and B2M | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
32.1 kDa (FCGRT) and 11.7 kDa (B2M) | |
Rabbit FCGRT&B2M; Heterodimer Protein, His Tag&Tag; Free (SPR verified) (FCM-R52W5) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Val 297 (FCGRT) and Val 22 - Tyr 120 (B2M) (Accession # ABY47597.1 (FCGRT) and ALR85722.1 (B2M)). | |
-20°C | |
FcRn (FCGRT and B2M) | |
Rabbit | |
PBS, pH7.4 | |
HEK293 | |
MABSol™ Fc Receptors |