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  6. TdB Labs AB 20 kDa FITC-DEAE-dextran Green Fluorophore

TdB Labs AB 20 kDa FITC-DEAE-dextran Green Fluorophore

Artikelnummer. 30216335
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Menge:
100 mg
1 g
Packungsgröße:
1 Gramm
100 Milligramm
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Artikelnummer. 30216335

Marke: TdB Labs AB FDD20_100mg

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Beschreibung

FITC-DEAE-dextran 20 kDa is a green-fluorescent, cationic polysaccharide used in transfection studies, nucleic acid complexation, and charge-based assays. Its size supports efficient uptake and molecular interaction analysis.

  • Product Overview: FITC-DEAE-dextrans are diethylaminoethyl-modified dextrans conjugated with fluorescein isothiocyanate (FITC), providing a green-fluorescent, cationic polysaccharide ideal for studies of electrostatic interactions, molecular complexation, and cellular uptake. Their positive charge, combined with bright fluorescence, makes FITC-DEAE-dextrans valuable tools in cell biology, drug delivery research, and membrane permeability studies.
  • Features:
    • Stable Green Fluorescence: Excitation at 495 nm and emission at 519 nm, compatible with standard FITC detection systems.
    • Positive Surface Charge: DEAE-modification imparts a strong cationic character, supporting binding to negatively charged membranes, proteins, and nucleic acids.
    • Water-Soluble and Biocompatible: Soluble in aqueous solutions, ready for immediate use in biological experiments.
    • Available in Multiple Molecular Weights: Offered in different sizes to suit applications involving cellular transport, binding studies, and permeability analysis.
    • Controlled Labeling: Manufactured under tight specifications to maintain optimal fluorescence intensity and reproducibility between batches.
  • Benefits:
    • Supports Cellular Uptake Studies: Cationic charge enhances uptake by endocytosis, useful for modeling drug delivery and nanoparticle entry into cells.
    • Ideal for Electrostatic Binding Research: Facilitates investigation of interactions between positively charged polymers and anionic biological targets.
    • Useful in Membrane Permeability Models: Applied to study transport and binding behavior at biological barriers, including epithelial and endothelial layers.
    • Bright and Reliable Detection: FITC labeling provides a strong, standardized signal suitable for microscopy, flow cytometry, and plate-based assays.
    • Flexible Application Range: Used across research fields including cell biology, biophysics, drug delivery, and materials science.
  • Applications:
    • Cellular Uptake and Endocytosis Studies: Traces the internalization pathways of cationic macromolecules in live cells.
    • Electrostatic Interaction Studies: Used to model binding between charged biomolecules and surfaces.
    • Barrier Permeability Research: Assesses transport behavior across polarized cell layers and tissue models.
    • Drug Delivery System Modeling: Simulates the behavior of cationic carriers in biological systems for targeted delivery applications.
    • Surface Coating and Modification Studies: Investigates how positively charged molecules interact with functionalized materials and biosurfaces.
  • Technical Specifications:
    • Fluorescence: Excitation maximum at 495 nm, emission maximum at 519 nm.
    • Molecular Weights: Available in standard dextran sizes modified with DEAE groups; specific molecular weights tailored to application needs.
    • Appearance: Light-sensitive, greenish dry powder, readily soluble in water.
    • Charge Density: Strong positive charge due to DEAE functionalization supporting binding to anionic targets.
  • Storage and Stability:
    • Store dry, protected from light, at 2°C to 8°C to maintain fluorescence and functionality.
    • Stable under recommended conditions for extended storage without significant loss of performance.
  • Packaging and Availability:
    • Supplied as dry powder for long-term stability and ease of handling.
    • Available in a variety of pack sizes to support both small research projects and larger studies.

Spezifikation

Menge 100 mg
Produkttyp Fluorescent Labeling Reagent
Molekulargewicht 20 kDa
Markertyp Other Labels or Dyes
Farbe Green
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