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ACROBiosystems ActiveMax™ Human LIF Protein, Tag Free

Marke:  ACROBiosystems LIF-H521B-50UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15887267

  • 342.14 € / 50 Mikrogramm
Verfügbar ab: 06-01-2023
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Beschreibung

Beschreibung

Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.

This protein carries no "e;tag"e;. The protein has a calculated MW of 19.9 kDa. The protein migrates as 33-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAH69540.1
19.9 kDa
50 µg
Ser 23 - Phe 202
LIF,CDF,DIA,HILDA,MLPLI
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
ActiveMax™ Human LIF, Tag Free (LIF-H521b) is expressed from human 293 cells (HEK293). It contains AA Ser 23 - Phe 202 (Accession # AAH69540.1).
-20°C
LIF
Tag Free
Less than 1.0 EU / µg by the LAL method.
ActiveMax™ Cytokines
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Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

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