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alpha Internexin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA110017
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
In Western blot, a prominent band at ∽66 kDa is observed, as well as smaller lower bands which are apparently degradation products. A minor band at ∽150 kDa is also seen, resulting from dimerization of alpha-internexin.
alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. Many classes of mature neurons contain a-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons a-internexin is the only neurofilament subunit expressed. Antibodies to internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of a-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage. The use of antibodies to this protein in the study of brain tumors has not been examined to date, but is likely to be of interest.Spezifikation
alpha Internexin | |
Polyclonal | |
Unconjugated | |
INA | |
66 kDa neurofilament protein; Alpha-internexin; alpha-Inx; AV028420; FLJ18662; FLJ57501; Ina; Inexa; internexin neuronal intermediate filament protein alpha; internexin neuronal intermediate filament protein, alpha; internexin, alpha; Intlaa; LOW QUALITY PROTEIN: alpha-internexin; MGC12702; NEF5; Neuro; Neurofilament 5; neurofilament 5 (66kD); Neurofilament 66; neurofilament-66; neurofilament-66, tax-binding protein; Nf66; NF-66; TXBP-1 | |
Rabbit | |
100 μL | |
Primary | |
Bovine, Equine, Human, Mouse, Porcine, Rat | |
Antibody | |
IgG |
Immunocytochemistry, Immunohistochemistry, Western Blot | |
Conc. Not Determined | |
whole serum with 5mM sodium azide | |
P23565, P46660, Q08DH7, Q16352 | |
INA | |
Purified, recombinant rat alpha-internexin, expressed in E. coli. | |
RUO | |
100059769, 100153400, 226180, 24503, 532236, 9118 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |