missing translation for 'onlineSavingsMsg'
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ASIC1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marque: Invitrogen OSR00097W
Informations supplémentaires : Netto-Gewicht : 0.01000kg
Description
Reconstitute with 100 μL of distilled water. Centrifuge to remove any insoluble material.
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown. Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. ASIC1 is permeable for Ca(2+), Li(+) and K(+) and is expressed in dorsal root ganglia, sciatic nerves, olfactory bulb, neo and allocortical regions, dentate granule cells, pyramidal cells of CA1-CA3 subfields of the hippocampal formation, habenula, basolateral amygdaloid nuclei, and in the Purkinje and granule cells of the cerebellum. It is diffusely detected over most other regions of the basal ganglia, including thalamic nuclei, substantia nigra, striatum and globus pallidus, hypothalamus, midbrain, pons, medulla and choroid plexus. Isoform 3 is expressed only in dorsal root ganglion while isoform 1 is expressed in DRG, spinal chord, trigeminal ganglia and the trigeminal mesencephalic nucleus.Spécification
ASIC1 | |
Polyclonal | |
ASIC1 | |
Acid-sensing ion channel 1, ASIC1, Brain sodium channel 2, BNaC2, ACCN2 | |
Rabbit | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Immunohistochemistry, Western Blot | |
Unconjugated | |
P78348, Q6NXK8, P55926 | |
ASIC1 | |
A synthetic peptide from the extracellular domain of human amiloride sensitive cation channel 2, neuronal | |
RUO | |
11419, 41, 79123 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Lyophilized |