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basic FGF Mouse, Unlabeled, Clone: 6, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 610073

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15885239

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Beschreibung

Beschreibung

Basic Fibroblast Growth Factor (bFGF) is a family member of the cell-differentiating and growth promoting factors. Basic FGF exists as multiple isoforms ranging from 18-24kDa that are derived from a single mRNA species under unique translational conditions. The 18kDa isoform is primarily cytosolic, but is also secreted and may form reservoirs of bFGF in the extracellular matrix. In contrast, the larger isoforms are predominantly nuclear. At the cellular level, bFGF is a potent mitogen and promotes cell survival by inhibiting apoptosis. At the tissue level, it is involved in wound repair and induces angiogenesis. In addition, bFGF is a significant target in cancer research because it is over-expressed in some cancers and may enhance a tumor's metastatic potential.

Host Species: Mouse
Clone: 6
Isotype: IgG1
Species Reactivity: Rat
Immunogen: Human bFGF aa. 1-155
Formula Weight [Chemical]: 18-24kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

basic FGF
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Human bFGF aa. 1-155
150 μg
Cell Biology
Canine, Chicken, Human, Mouse, Rat
IgG2a
Western Blot
6
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.