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CD16 Mouse anti-Human, Brilliant Violet 421, Clone: 3G8, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 562878
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.
Host Species: Mouse
Clone: 3G8
Isotype: IgG1, κ
Species Reactivity: Hu
Immunogen: Human polymorphonuclear leukocytes
Flow Cytometry
Spezifikation
| CD16 | |
| Monoclonal | |
| Brilliant Violet 421 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human polymorphonuclear leukocytes | |
| 25 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| 3G8 | |
| FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Baboon, Cynomolgus, Human, Rhesus Monkey | |
| IgG1 κ |
For Research Use Only.