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CD25 Mouse anti-Human, Brilliant Violet 786, Clone: M-A251, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 563700
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2R α ). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2R β /CD122 and the IL-2R γ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2R α is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.
Spezifikation
CD25 | |
Monoclonal | |
Brilliant Violet 786 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Affinity Purified | |
RUO | |
Human | |
IgG1 κ |
Flow Cytometry | |
M-A251 | |
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55 | |
Mouse | |
25 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.