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CD28 Mouse anti-Human, PE-CF594, Clone: CD28.2, BD
Mouse Monoclonal Antibody
243.00 € - 650.00 €
Spezifikation
Antigen | CD28 |
---|---|
Klon | CD28.2 |
Anwendungen | Flow Cytometry |
Klassifikation | Monoclonal |
Konjugat | PE-CF594 |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15851819
|
BD Biosciences
562323 |
25 Tests |
243.00 €
1 Stück |
Verfügbar ab: 23-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
15881789
|
BD Biosciences
562296 |
100 Tests |
650.00 €
1 Stück |
Verfügbar ab: 23-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
The CD28.2 monoclonal antibody specifically binds to CD28, a 44 kDa homodimeric transmembrane glycoprotein present on most mature T cells, thymocytes and plasma cells. CD28 is a costimulatory receptor that binds CD80 and CD86 as ligands and plays a very important role in T cell-B cell interactions. It has been suggested that CD28 initiates and regulates a separate and distinct signal transduction pathway from those stimulated by the TCR complex. Additionally, it has been reported that CD28 antibody clones vary in their ability to stimulate T cells to produce IL-2 and increase intracellular Ca2+ concentration. This finding suggests the existence of functionally distinct subregions on the CD28 molecule. CD28.2 has been demonstrated to bind to the same molecule as clone L293, another CD28 mAb, and has been reported to induce Ca2+ influx in Jurkat T cells.
This antibody is conjugated to BD Horizon PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg, 610/20-nm filter).
Spezifikation
CD28 | |
Flow Cytometry | |
PE-CF594 | |
RUO | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
IgG1 κ | |
Affinity Purified | |
CD28 antigen; T44; Tp44; TP44 |
CD28.2 | |
Monoclonal | |
Mouse | |
Human | |
DC28.1.3.3 hybridoma cells | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.