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CD59 Mouse anti-Human, FITC, Clone: P282 (H19), BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 555763
Weitere Details : Netto-Gewicht : 0.02000kg
Beschreibung
The p282 (HI9) monoclonal antibody specifically binds to CD59, a 19 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein, expressed on hematopoietic and non-hematopoietic cells. Because of its role in interaction with complement activated products, CD59 has been termed membrane-attack-complex-inhibitory factor (MACIF), homologus restriction factor (HRF20), membrane inhibitor of reactive lysis (MIRL) and Protectin. It inhibits the cytolytic activity of complement by binding to C8 and C9, thereby blocking the assembly of the membrane attack complex. CD59 also participates in spontaneous T-cell/erythrocyte adhesion, interacts with CD2 and plays a role in T-cell activation.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Spezifikation
| CD59 | |
| Monoclonal | |
| FITC | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| P282 (H19) | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human Erythrocytes | |
| 100 Tests | |
| Immunology | |
| Human | |
| IgG2a κ |
For Research Use Only.