Learn More
IL21R Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA519983
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
In Western blot applications, this antibody detects a band at ∽60kDa. A suggested positive control is Raji cell lysate. PA5-19983 can be used with blocking peptide PEP-0107.
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.Spezifikation
IL21R | |
Polyclonal | |
Unconjugated | |
Il21r | |
CD360; IL-21 receptor; Il21r; IL-21R; interleukin 21 receptor; interleukin-21 receptor; LR-beta; lymphocyte receptor beta; MGC10967; NILR; novel cytokine receptor 8; Novel interleukin receptor; NR8; UNQ3121/PRO10273 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
308977, 50615, 60504 | |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
Q9HBE5, Q9JHX3 | |
Il21r | |
A synthetic peptide corresponding to amino acids 20 to 32 of human IL-21 receptor precursor. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |