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IL-34 Recombinant Rabbit Monoclonal Antibody (2H3L6), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Marke: Invitrogen 701089
Weitere Details : Netto-Gewicht : 0.00450kg
Beschreibung
Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.Spezifikation
IL-34 | |
Recombinant Monoclonal | |
0.5 mg/mL | |
PBS with 0.09% sodium azide | |
Q6ZMJ4 | |
Il34 | |
Recombinant protein corresponding to amino acids 133–242 of human interleukin 34 | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
Western Blot | |
2H3L6 | |
Unconjugated | |
Il34 | |
2010004A03Rik; AI593503; C16orf77; IL34; IL-34; ILN; Interleukin; interleukin 34; Interleukin34; interleukin-34 | |
Rabbit | |
Protein A | |
RUO | |
146433 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |