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p150 [Glued] Mouse, Unlabeled, Clone: 1, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 610473

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15895479

  • 403.56 € / 1 Set
Verfügbar ab: 19-12-2022
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Beschreibung

Beschreibung

p150 [Glued] was identified as a polypeptide associated with cytoplasmic dynein, the minus-end-directed microtubule-based motor protein. p150 [Glued] is also a member of the oligomeric dynactin complex. Dynactin mediates dynein-driven vesicle motility, as well as lower eukaryote nuclear transport. p150 [Glued] bears significant homology to the product of the Glued gene in Drosophila. It has been shown in vitro to be a required activator of dynein-mediated transport along microtubules. The p150 [Glued] component of the dynactin complex binds to microtubules and the actin-like protein Centractin (Arp-1), another member of the dynactin complex. In the developing rat, p150 [Glued] is expressed at high levels in neural tissue. Microtubule bindings assays with selected constructs of p150 [Glued] indicate that amino acids 39-150 are required for microtubule association.

This antibody is routinely tested by western blot analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Spezifikation

Spezifikation

p150 [Glued]
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
50 μg
Cell Biology
Rat, Mouse, Human, Chicken, Canine
IgG1
Western Blot
1
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
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Sicherheitsdatenblatt (SDS)
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Sonderangebote

Sonderangebote

For Research Use Only.