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PCNA Mouse, Unlabeled, Clone: 24, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 610665

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15895569

  • 605.34 € / 1 Set
Verfügbar ab: 03-01-2023
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Beschreibung

Beschreibung

Progression of the mammalian cell cycle is regulated in two different ways: 1) phosphorylation and dephosphorylation of key proteins, 2) synthesis and degradation of regulatory factors. The Proliferating Cell Nuclear Antigen (PCNA) was initially identified as a nuclear antigen in proliferating cells and was subsequently described as a subunit for DNA polymerase δ. Human PCNA is 262 amino acids with an apparent molecular weight of 36kDa. PCNA protein levels peak during the S-phase of the cell cycle, at which time it forms a complex with the p21 inhibitor. PCNA is almost undetectable in other phases of the cycle. Because of its unique expression, PCNA has been extensively used in studies associating the prognosis of tumor progression and neoplastic proliferation.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

PCNA
Monoclonal
250μg/mL
Proliferating Cell Nuclear Antigen
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Western Blot
24
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
150 μg
Cell Biology
Rat, Mouse, Human, Canine
IgG1
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.