missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Phospho-ERK1/ERK2 (Tyr204) Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen LFPA0090
Weitere Details : Netto-Gewicht : 0.99000kg
Beschreibung
A suggested positive control for this product is NIH-3T3 cell treated with PDGF-BB.
ERK1 and ERK2 are widely expressed and are involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. When growth factors bind to the receptor tyrosine kinase, Ras interacts with Raf, the serine/threonine protein kinase and activates it as well. Once actived, Raf phosphorylates serine residue in 2 further kinases, MEK1/2, which in turn phosphorylates tyrosine/threonine in extracellular-signal regulated kinase (ERK) 1/2. Upon activation, the ERKs either phosphorylate a number of cytoplasmic targets or migrate to the nucleus, where they phosphorylate and activate a number of transcription factors such as c-Fos and Elk-1.Spezifikation
Phospho-ERK1/ERK2 (Tyr204) | |
Polyclonal | |
MAPK1 | |
Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2 , MAPK1, ERK2, PRKM1, PRKM2, Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p44-ERK1, MAPK3, ERK1, PRKM3, p44, p42 | |
Rabbit | |
Ammonium sulfate precipitation | |
RUO | |
116590, 26413, 26417, 50689, 5594, 5595 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
Unconjugated | |
P27361, P28482, P63085, Q63844, P21708, P63086 | |
MAPK1, MAPK3 | |
Synthetic phospholyrated peptide (KLH coupled) corresponding to residues around Thr202/Tyr204 of human p44 MAP kinase (Erk1). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |