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Phospho-Tau (Ser214) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen 44742G
Weitere Details : Netto-Gewicht : 0.50000kg
Beschreibung
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Phospho-Tau (Ser214) Polyclonal antibody specifically detects Phospho-Tau (Ser214) in Human, Mouse, Rat samples. It is validated for Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot.Spezifikation
| Phospho-Tau (Ser214) | |
| Polyclonal | |
| Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3 | |
| P10636, P10637, P19332 | |
| MAPT | |
| The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human Tau that contains serine 214. The sequence is conserved in many species including mouse, rat, rhesus monkey, baboon, cow and goat. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| MAPT | |
| AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287) | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 17762, 29477, 4137 | |
| -20°C | |
| Liquid |