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PIN Mouse, Unlabeled, Clone: 4, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 610726

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15885609

  • 308.94 € / 1 Set
Verfügbar ab: 02-01-2023
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Beschreibung

Beschreibung

PIN (protein inhibitor of nNOS) is a small protein of 89 amino acids initially described as a light chain subunit of dynein and as an inhibitor of the neuronal nitric oxide synthase isoform (nNOS). In vitro, PIN has been reported to bind to a unique nNOS domain encompassing amino acids 163-245. PIN inhibits nNOS activity and blocks the formation of the active nNOS dimer. Although ubiquitously expressed, PIN levels are reportedly highest in brain and testis. Immunolocalization studies in Drosophila melanogaster detected a cytoplasmic distribution of PIN. Partial-loss-of-function of PIN resulted in morphologic and developmental changes in the bristles, wings, and female sterility of D. melanogaster. Deletion of PIN resulted in lethality with the characteristic morphology of apoptotic cells.

Immunofluorescence, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

PIN
Monoclonal
250μg/mL
Protein Inhibitor of nNOS
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Western Blot, Immunofluorescence
4
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Rat PIN aa. 1-89
50 μg
Cell Biology
Rat, Human
IgG1
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.