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PIST Polyclonal Antibody, Invitrogen™
Goat Polyclonal Antibody
Marke: Invitrogen PA518240
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
This antibody is predicted to react with bovine and canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.Spezifikation
| PIST | |
| Polyclonal | |
| Unconjugated | |
| GOPC | |
| 2210402P09Rik; AI844555; CAL; CFTR-associated ligand; dJ94G16.2; dJ94G16.2 PIST; FIG; Fused in glioblastoma; golgi associated PDZ and coiled-coil motif containing; Golgi associated PDZ and coiled-coil motif containing protein; golgi-associated PDZ and coiled-coil motif containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; Gopc; GOPC1; PDZ domain-containing protein PIST; PDZ protein interacting specifically with TC10; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10; PIST | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 57120 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunocytochemistry, Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q9HD26 | |
| GOPC | |
| Synthetic peptide sequence (LDDLHTLYHKKSY) corresponding to the C-terminus amino acids of GOPC | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |