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PKA[C] Mouse, Unlabeled, Clone: 5B, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 610981

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 15885739

  • 696.54 € / 1 Set
Verfügbar ab: 19-12-2022
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Beschreibung

Beschreibung

cAMP-dependent Protein Kinase (PKA) is composed of two distinct subunits: catalytic (C) and regulatory (R). Four regulatory subunits have been identified: RIα, RIβ, RIIα, and RIIβ. These subunits define type I and II cAMP-dependent protein kinases. Following binding of cAMP, the regulatory subunits dissociate from the catalytic subunits, rendering the enzyme active. Type I and type II holoenzymes have three potential C subunits (Cα, Cβ, or Cγ). Type II PKA can be distinguished by autophosphorylation of the R-subunits, while type I PKA binds Mg/ATP with high affinity. The levels of expression of the different subunits vary according to cell and tissue type.

Immunofluorescence, Western Blotting

Spezifikation

Spezifikation

PKA[C]
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Human PKA[Cα] subunit aa. 18-347
150 μg
Cell Biology
Rat, Mouse, Human, Canine
IgG2b
Western Blot
5B
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.