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Plasminogen Polyclonal Antibody, Biotin, Invitrogen™
Goat Polyclonal Antibody
Marke: Invitrogen PA126883
Weitere Details : Netto-Gewicht : 0.01000kg
Description
PA1-26883 detects Plasminogen from human samples.
Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70 - 200 mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Plasmin consists of a heavy (A-) chain which contains 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles. Plasmin is essential for fibrinolysis and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis and pulmonary embolism.Spécification
Plasminogen | |
Polyclonal | |
Biotin | |
PLG | |
Ab1-346; Activation peptide; AI649309; angiostatin; DKFZp779M0222; Pg; plasmin; plasmin heavy chain A; Plasmin heavy chain A, short form; Plasmin light chain B; plasminogen; PLG; RP1-81D8.1 | |
Goat | |
IgG fraction | |
RUO | |
5340 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Western Blot | |
10 mg/mL | |
0.02M potassium phosphate with 0.15M NaCl, 10mg/mL BSA and 0.01% sodium azide; pH 7.2 | |
P00747 | |
PLG | |
Plasminogen from human plasma. | |
1 mg | |
Primary | |
Human | |
Antibody | |
IgG |