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Beta Arrestin 2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00 € - 399.00 €
Spezifikation
Antigen | Beta Arrestin 2 |
---|---|
Konzentration | 0.27 mg/mL |
Anwendungen | Western Blot, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunocytochemistry |
Klassifikation | Polyclonal |
Konjugat | Unconjugated |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
16886373
|
Proteintech
10171-1-AP-20UL |
20 μL |
140.00 €
20 Mikroliter |
Verfügbar ab: 21-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
16876373
|
Proteintech
10171-1-AP-150UL |
150 μL |
399.00 €
150 Mikroliter |
Verfügbar ab: 21-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Beta-arrestin-2, or ARRB2, is an adaptor protein belonging to the arrestin family with an N- arrestin domain and a C- arrestin domain. ARRB2 is a regulatory protein involved in heterotrimeric G protein-coupled receptor desensitization and is known to regulate beta2-adrenergic receptor (beta2AR) function by enhancing beta2AR mediated nuclear translocation of ERK. ARRB2 binds to phosphorylated beta2ARs, thereby causing a significant impairment of their capacity to activate G(S) proteins. Along with AIP4, ARRB2 acts as an endosomal sorting molecule that mediates CXCR4 entry into a degradative pathway. It may also be involved in hormone-specific desensitization of TSH receptors. ARRB2 is a Ca2+ binding protein of the retinal outer segments and binds to P-rhodopsin and is also involved in synaptic transmission in photoreceptor cells. It is widely expressed in most of the tissues, especially neuronal tissues and spleen.Spezifikation
Beta Arrestin 2 | |
Western Blot, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunocytochemistry | |
Unconjugated | |
Rabbit | |
Mouse, Human | |
P32121, Q91YI4 | |
216869, 409 | |
Beta Arrestin 2 Fusion Protein Ag0227 | |
Primary | |
-20°C | |
ARRB2 |
0.27 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
ARB2, ARR2, ARRB2, Arrestin beta 2, arrestin, beta 2, BARR2, Beta arrestin 2 | |
ARRB2 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |