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ACROBiosystems Biotinylated Human B7-H6 / NCR3LG1 Protein, Fc, Avitag™
Biotinylated Protein
423.38 € - 1862.87 €
Spezifikation
| Zugriffsnummer | NP 001189368.1 |
|---|---|
| Molekulargewicht | 54.8 kDa |
| Quelle | Biotinylated Human B7-H6, Fc,Avitag (B76-H82Wb) is expressed from human 293 cells (HEK293). It contains AA Asp 25 - Ser 262 (Accession # Q68D85-1). |
| Immunogen | Asp 25 - Ser 262 |
| Lagerungsbedingungen | -20°C |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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17126081
|
ACROBiosystems
B76-H82WB-25UG |
25 μg |
423.38 €
25 Mikrogramm |
Verfügbar ab: 07-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
17116081
|
ACROBiosystems
B76-H82WB-200UG |
200 μg |
1862.87 €
200 Mikrogramm |
Verfügbar ab: 07-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
The B7 family of genes is essential in the regulation of the adaptive immune system. one of which is the recently discovered B7H6. Humans and rats have a single B7H6 gene; however, many B7H6 genes were detected in a single large cluster in the Xenopus genome. Chimeric antigen receptor (CAR) T-cell therapies have demonstrated durable and potentially curative therapeutic efficacy against B-cell leukemia in clinical trials. In this study, B7H6, a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.
This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 54.8 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP 001189368.1 | |
| Biotinylated Human B7-H6, Fc,Avitag (B76-H82Wb) is expressed from human 293 cells (HEK293). It contains AA Asp 25 - Ser 262 (Accession # Q68D85-1). | |
| -20°C | |
| B7-H6 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |
| 54.8 kDa | |
| Asp 25 - Ser 262 | |
| B7-H6,NCR3LG1,B7 Homolog 6 | |
| Precision Avi | |
| Fc Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |