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ACROBiosystems Biotinylated Human LOXL2 Protein, His, Avitag™
Biotinylated Protein
423.38 € - 1681.42 €
Spezifikation
| Molekulargewicht | 87.8 kDa |
|---|---|
| Quelle | Biotinylated Human LOXL2, His,Avitag (LO2-H82E3) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Gln 774 (Accession # Q9Y4K0-1). |
| Immunogen | Gln 26 - Gln 774 |
| Lagerungsbedingungen | -20°C |
| Gen-Alias | Lysyl oxidase homolog 2,LOXL2 |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
16477849
|
ACROBiosystems
LO2-H82E3-25UG |
25 μg |
423.38 €
25 Mikrogramm |
Verfügbar ab: 04-06-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
16467849
|
ACROBiosystems
LO2-H82E3-200UG |
200 μg |
1681.42 €
200 Mikrogramm |
Verfügbar ab: 04-06-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Lysyl oxidase homolog 2 is also known as LOXL2, Lysyl oxidase-like protein 2, which is expressed in many tissues, highest expression in reproductive tissues, placenta, uterus and prostate, Up-regulated in a number of cancers cells and tissues. LOXL2 mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. LOXL2 acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. LOXL2 acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 87.8 kDa.Spezifikation
| 87.8 kDa | |
| Gln 26 - Gln 774 | |
| Lysyl oxidase homolog 2,LOXL2 | |
| Precision Avi | |
| His Tag and Avi Tag | |
| Powder | |
| PBS, pH7.4 |
| Biotinylated Human LOXL2, His,Avitag (LO2-H82E3) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Gln 774 (Accession # Q9Y4K0-1). | |
| -20°C | |
| LOXL2 | |
| Human | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |