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C17orf85 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Thermo Scientific PA552633
Weitere Details : Netto-Gewicht : 0.02000kg
Beschreibung
Immunogen sequence: LRVSVKAEAP AGPALGLPSP EAESGVDRGE PEPMEVEEGE LEIVPVRRSL KELIPDTSRR YENKAGSFIT GIDVTSKEAI EKKEQRAKRF HFRSEVNLAQ RNVALDRDMM KKAIPKVRLE TIYICGVD Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth.Spezifikation
| C17orf85 | |
| Polyclonal | |
| Unconjugated | |
| NCBP3 | |
| 1200014J11Rik; C11H17orf85; C130061O14Rik; C17orf85; C19H17orf85; C78393; C9H17orf85; CTD-3195I5.1; CTD-3195I5.5; ELG; ELG protein; HSA277841; Ncbp3; nuclear cap binding subunit 3; nuclear cap-binding protein subunit 3; Protein ELG; RGD1308139; RIKEN cDNA 1200014J11 gene; similar to RIKEN cDNA 1200014J11; uncharacterized protein C17orf85 homolog | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 55421 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q53F19 | |
| NCBP3 | |
| Recombinant protein corresponding to Human C17orf85 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only