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CD127 Mouse anti-Human, Alexa Fluor 647, Clone: HIL-7R-M21, BD
Mouse Monoclonal Antibody
270.00 € - 530.00 €
Spezifikation
| Antigen | CD127 |
|---|---|
| Klon | HIL-7R-M21 |
| Anwendungen | Flow Cytometry |
| Klassifikation | Monoclonal |
| Konjugat | Alexa Fluor 647 |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15890579
|
BD Biosciences
560905 |
25 Tests |
270.00 €
1 Stück |
Verfügbar ab: 10-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
15809518
|
BD Biosciences
558598 |
100 Tests |
530.00 €
1 Stück |
Verfügbar ab: 06-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
The hIL-7R-M21 monoclonal antibody specifically binds to the 60-90 kDa glycoprotein, CD127. CD127 is also known as the IL-7 receptor alpha (IL-7Rα) subunit. The IL-7 receptor complex is a heterodimer composed of CD127 and the common gamma chain (γc, CD132), shared by other cytokine receptors (IL-2R, IL-4R, IL-9R, IL-15R, and IL-21R). CD127 is expressed on thymocytes, T- and B-cell progenitors, mature T cells, and some lymphoid and myeloid cells. In vitro experiments show the expression of CD127 is down-regulated following T cell activation. Studies indicate that the IL-7 Receptor plays an important role in the proliferation and differentiation of mature T cells. Recently, it has been shown that low surface expression of CD127, in combination with intermediate to high surface expression of CD25, the α chain of the IL-2 receptor complex, can distinguish between human regulatory and conventional CD4+ T cells in human adult and cord blood, lymph nodes and thymus.
Spezifikation
| CD127 | |
| Flow Cytometry | |
| Alexa Fluor 647 | |
| RUO | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| IgG1 κ | |
| Affinity Purified | |
| IL-7R; IL7R; IL7RA; IL-7Rα; IL-7R-alpha; Interleukin-7 Receptor alpha |
| HIL-7R-M21 | |
| Monoclonal | |
| Mouse | |
| Human | |
| Human IL-7R Recombinant Protein | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.