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CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Marke: Invitrogen 16-0731-050
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Beschreibung
eBioTY/11.8 recognizes the with CD73 a 69-kDa GPI-anchored cell-surface protein with ecto-5'-nucleotidase activity. Expression on myeloid cells (CD11b) is restricted to the bone marrow. In human CD73 can be induced to secrete a soluble form with IL-2 suggesting a role in mediating activation signals. Differences between human and mouse CD73 have been reported. BALB/c mice have more CD4+CD73+ than CD8+CD73+ while the reciprocal is documented in humans. CD73 is expressed on a subset of lymphocytes and increases during lymphocyte maturation. Recently it has been found that memory CD4 T cells express and are similar to the uncommitted primed precursor helper cells (Thpp) that can differentiate into Th1 or Th2 cells. Furthermore CD73 has been found on regulatory T cells.
CD73 Monoclonal antibody specifically detects CD73 in Mouse samples. It is validated for Control, Flow Cytometry, Functional Assay
Spezifikation
| CD73 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative; pH 7.2 | |
| Q61503 | |
| Rat | |
| 50 mg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Functional Assay | |
| eBioTY/11.8 (TY/11.8) | |
| Functional Grade | |
| NT5E | |
| 2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; Ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; Nte; Purine 5-Prime-Nucleotidase | |
| Affinity chromatography | |
| RUO | |
| 23959 | |
| 4° C | |
| Liquid |
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