Learn More
CD80 Hamster anti-Mouse, FITC, Clone: 16-10A1, BD
Hamster Monoclonal Antibody
255.00 € - 433.00 €
Spezifikation
Antigen | CD80 |
---|---|
Klon | 16-10A1 |
Konzentration | 0.5mg/mL |
Anwendungen | Flow Cytometry |
Klassifikation | Monoclonal |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15891499
|
BD Biosciences
561954 |
0.1 mg |
255.00 €
1 Stück |
Verfügbar ab: 23-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
15867378
|
BD Biosciences
553768 |
0.5 mg |
433.00 €
1 Stück |
Verfügbar ab: 23-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
The 16-10A1 antibody reacts with CD80 (B7-1). This member of the Ig superfamily, along with CD86 (B7-2), participates in T-cell co-stimulation via interactions with CD28 and CD152 (CTLA-4). CD80 has been reported to be constitutively expressed on dendritic cells, monocytes, and peritoneal macrophages; and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 has been reported to be greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that the activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours. The 16-10A1 antibody has been reported to block binding of CTLA-4 Ig to CD80 and to block T-cell activation by Con A-elicited peritoneal exudate cells and CD80-transfected cell lines. However, 16-10A1 antibody alone is not able to block T-cell activation by antigen-presenting cells. CD86 (B7-2) is an alternate ligand for CD28 and CD152 (CTLA-4). Preliminary reports indicate that the 16-10A1 mAb may block the binding of rat anti-CD80 mAb clone 1G10 (Mfr. No. 553368). In addition, it has been reported that the 16-10A1 antibody may cross-react with an activation antigen expressed on IFN-γ-activated alveolar macrophages of the dog.
Host Species: Hamster
Clone: 16-10A1
Isotype: IgG2 κ
Species Reactivity: Mouse
Immunogen: Mouse CD80 (B7) Transfected Cell Line
Flow Cytometry
Spezifikation
CD80 | |
0.5mg/mL | |
Monoclonal | |
Hamster | |
Mouse | |
Mouse CD80 (B7) Transfected Cell Line | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
16-10A1 | |
Flow Cytometry | |
FITC | |
RUO | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
IgG2 κ | |
Affinity Purified | |
Cd80; B7; B7-1; Cd28l; Ly-53; MIC17; TSA1 |
For Research Use Only.