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CD8a Mouse anti-Rat, Unconjugated, Clone: OX-8, Proteintech

Mouse Monoclonal Antibody

Marke:  Proteintech 65180-1-IG-100UG

Weitere Details : Netto-Gewicht : 0.00010kg

Artikelnummer. 17294636

  • 84.00 € / 100 Mikrogramm
Verfügbar ab: 10-02-2023
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Beschreibung

Beschreibung

CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells , on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084).

Spezifikation

Spezifikation

CD8a
Monoclonal
1 mg/mL
Mouse
Primary
Rat
Mouse IgG1 κ
Flow Cytometry
OX-8
Unconjugated
100 μg
24930
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote