CDH9 Polyclonal Antibody, Invitrogen™

Beschreibung

Immunogen sequence: GIITVKQNLD FENQMLYTLR VDASNTHPDP RFLHLGPFKD TAVVKISVED IDEPPVFTKV SYLIEVDEDV KEGSIIGQVT AYDPDARNNL IKYSVDRHTD MDRI Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.

CDH9 (cadherin-9) is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.