CIAO1 Rabbit anti-Human, Polyclonal, Proteintech

Beschreibung

10295-1-AP detected 48-55 kDa band because of phosphorylation. 10295-1-AP does well in IHC and IF detection.

WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.