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CIC Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA583721
Weitere Details : Netto-Gewicht : 0.01000kg
Beschreibung
Immunogen sequence: PKRKMRRRSS CSSEPNTPKS AKCEGDIFTF DRTGTEAEDV LGELEYDKVP YSSLRRTLDQ RRALVMQLFQ DHGFFPSAQA TAAFQARYAD IFPSKVCLQL KIREVRQKIM QA
CIC, a human homolog of Drosophila capicua, encodes a high mobility group box transcription factor and is fused to a double homeodomain gene DUX4 as a result of a recurrent chromosomal translocation. It is involved in epidermal growth factor receptor (EGFR) signaling, developmental patterning, and cell fate. In humans, CIC may be involved in granule cell lineage, cerebellar development, and medulloblastoma tumorigenesis. Recent evidence indicates that CIC is involved in Spinocerebellar Ataxia Type 1 (SCA-1) where it interacts directly with the product of the SCA-1 gene Ataxin-1.Spezifikation
| CIC | |
| Polyclonal | |
| Unconjugated | |
| CIC | |
| KIAA0306 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 23152 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q96RK0 | |
| CIC | |
| Recombit protein corresponding to Human CIC | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |