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DIDS, Tocris Bioscience™
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Menge:
50 mg
Beschreibung
ClC-Ka chloride channel blocker (IC50 = 100 μM). Blocks the maxi chloride channel in apical membranes from human placenta. Displays antagonistic activity at TRPM4 and TRPC4 channels; potentiates agonist-induced TRPV1 currents (IC50 = 4.88 μM in rat DRG neurons). Inhibits RAD51 recombinase activity (KD = 2 μM).
Spezifikation
| Chemischer Name oder Material | DIDS |
| CAS | 67483-13-0 |
| Summenformel | C16H8N2Na2O6S4 |
| Menge | 50 mg |
| Synonym | dids, unii-1vfrq7416a, disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulfonate, 4,4'-diisothiocyanato-2,2'-stilbenedisulfonic acid disodium salt, 4,4'-diisothiocyano-2,2'-stilbenedisulfonic acid, disodium salt, disodium 5-isothiocyanato-2-e-2-4-isothiocyanato-2-sulfonatophenyl ethenyl benzenesulfonate, spectrum1505164, 4 4'-diisothiocyanato-2 2'-stilbenedisu, disodium 4,4'-diisothiocyanatostilbene-2,2'-disulfonate, disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulfonate, e |
| InChI-Schlüssel | GEPAYBXVXXBSKP-SEPHDYHBSA-L |
| SMILES | C1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])C=CC2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-].[Na+].[Na+] |
| IUPAC-Name | disodium;5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfonatophenyl)ethenyl]benzenesulfonate |
| Molekulargewicht (g/mol) | 498.468 |
| PubChem CID | 5702690 |
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